Sun H, Jiang L, Luo X, Jin W, He Q, An J, Lui K, Shi J, Rong R, Su W,
Lucchesi CA, Liu Y, Sheikh MS, Huang Y. Potential tumor-suppressive role of monoglyceride lipase in human colorectal cancer. Oncogene, 32(2): 234-41

 

Zhang J, Lucchesi CA, Chen X. A new function for p53 tetramerization domain in cell fate control. Cell Cycle, 15(21): 2854-2855.

 

Lucchesi CA, Zhang J, Chen X. Modulation of the p53 family network by RNAbinding proteins. Transl Cancer Res, 5(6): 676-684.

 

Lucchesi CA, Sheikh MS, Huang Y. Negative regulation of RNA-binding protein HuR by tumor-suppressor ECRG2. Oncogene, 35(20): 2565-73.

 

Yang HJ, Zhang J, Yan W, Cho SJ, Lucchesi C, Chen M, Huang EC,
Scoumanne A, Zhang W, Chen X. Ninjurin 1 has two opposing functions in tumorigenesis in a p53-dependent manner. Proc Natl Acad Sci U S A,114(43): 11500-11505

 

Lucchesi CA, Zhang J, Ma B, Chen M, Chen X. Disruption of the Rbm38- eIF4E Complex with a Synthetic Peptide Pep8 Increases p53 Expression. Cancer Res, 79(4): 807-818.

 

Lucchesi CA, Zhang J, Ma B, Nussinov R, Chen X. Survivin Expression Is Differentially Regulated by a Selective Cross-talk between RBM38 and miRNAs let-7b or miR-203a. Cancer Res, 81(7): 1827-1839

 

Sun W, Laubach KN, Lucchesi CA, Zhang Y, Chen M, Zhang J, Chen X. Fine-Tuning p53 Activity by Modulating the Interaction between Eukaryotic Translation Initiation Factor eIF4E and RNA-Binding Protein RBM38. Genes Dev, 1(35): 542-555.

 

Toedebusch RG, Lucchesi CA, Debebe ET, Wittenburg LA, Chen X, Toedebusch CM. Microglia-Derived Olfactomedin-like 3 Promotes Pro-Tumorigenic Microglial Function and Malignant Features of Glioma Cells. Int J Mol Sci, 22(23): 13052.

 

Lucchesi CA, Zhang J, Vasilatis DM, Yip E, Chen X. Optimization of eIF4EBinding Peptide Pep8 to Disrupt the RBM38-eIF4E Complex for Induction of p53 and Tumor Suppression. Front Oncol, 12: 893062.

 

Lucchesi CA, Zhang J, Goa M, Shaw J, Chen X. Identification of a First-in-Class Small Molecule Inhibitor of the eIF4E-RBM38 Complex that Enhances wild-type p53 Protein Translation for Tumor Growth Suppression. MCT February  PMID: 36940176 DOI: 10.1158/1535-7163.MCT-22-0627

 

Vasilatis DM, Lucchesi CA, Ghosh PM. Molecular Similarities and Differences between Canine Prostate Cancer and Human Prostate Cancer Variants. Biomedicines. 2023 Apr 5;11(4):1100. doi: 10.3390/biomedicines11041100. PMID: 37189720; PMCID: PMC10136260.

2023

Steele TM, Tsamouri MM, Siddiqui S, Lucchesi CA, Vasilatis D, Mooso BA, Durbin-Johnson BP, Ma AH, Hejazi N, Parikh M, Mudryj M, Pan CX, Ghosh PM. Cisplatin-induced increase in heregulin 1 and its attenuation by the monoclonal ErbB3 antibody seribantumab in bladder cancer. Sci Rep. 2023 Jun 14;13(1):9617. doi: 10.1038/s41598-023-36774-1. PMID: 37316561; PMCID: PMC10267166.

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Lucchesi CA, Vasilatis DM, Mantrala S, Chandrasekar T, Mudryj M, Ghosh PM. Pesticides and Bladder Cancer: Mechanisms Leading to Anti-Cancer Drug Chemoresistance and New Chemosensitization Strategies. Int J Mol Sci. 2023 Jul 13;24(14):11395. doi: 10.3390/ijms241411395. PMID: 37511154; PMCID: PMC10380322.

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Zhang J, Kong X, Yang HJ, Mohibi S, Lucchesi CA, Zhang W, Chen X. Ninjurin 2, a Cell Adhesion Molecule and a Target of p53, Modulates Wild-Type p53 in Growth Suppression and Mutant p53 in Growth Promotion. Cancers. 2024; 16(1):229. https://doi.org/10.3390/cancers16010229

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Vasilatis DM, Batra N, Lucchesi CA, Abria CJ, Packeiser EM, Murua Escobar H, Ghosh PM. Alterations in Tumor Aggression Following Androgen Receptor Signaling Restoration in Canine Prostate Cancer Cell Lines. Int J Mol Sci. 2024 Aug 7;25(16). doi: 10.3390/ijms25168628. PubMed PMID: 39201315; PubMed Central PMCID: PMC11354774.

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Lucchesi CA, Mantrala S, Tran D, Batra N, Durve A, Suen C, Zhang J, Ghosh P, Chen X. ANGEL2 modulates wildtype TP53 translation and doxorubicin chemosensitivity in colon cancer. Mol Cancer Res. 2025 Mar 7;. doi: 10.1158/1541-7786.MCR-24-0702. PubMed PMID: 40052999; NIHMSID:NIHMS2066163.

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